Lewis Tem Bueh

Lewis Tem Bueh

AI/ML Researcher, Healthcare, Software Developer

Discover my research, projects and experiences in the world of AI and software development. I forge new paths and create innovative solutions to the most complex problems, defining what is possible with AI, healthcare and technology.

Who I Am

About Me

I am a Masters student in Data Science at the University of Buea and a skilled software engineer based in Buea, Cameroon. My passion lies at the intersection of AI and Healthcare, where I strive to build responsible solutions for real-world problems.

With a strong foundation in Machine Learning and Bioinformatics, I have contributed to impactful research in drug discovery and disease prediction. I am also the founder and Lead of Data Science Hub (DSH), a community at the intersection of AI and Sustainability engaging students in collaborative learning and real-world applications. Cultivating the next generation of African AI leaders to drive a new era continental innovation.

I am driven by curiosity and a commitment to excellence, defining whats possible with AI Research in Africa and beyond. I am always eager to connect with like-minded individuals and explore new opportunities to make a positive impact through technology.

Expertise

Technical Skills

Programming Languages

Python (+ Django, Flask)C/C++JavaJavaScriptReactJSReact-Native

Machine Learning/AI

NumPyPandasMatplotlibSeabornScikit-learnPyTorchTensorFlowKerasOpenCVXGBoostLightGBMOptunaSHAP

Bioinformatics

AutoDock VinaGROMACSPaDELRDKitPyMOLLigPlot+SwissADME

Data Science

Feature EngineeringDimensionality ReductionCross-ValidationHyperparameter TuningModel Interpretability

Databases

MySQLPostgreSQLFirebaseNeon

Tools

GitGitHubVS CodeJupyter NotebookJiraDocker

Career Path

Work Experience

Codeathon Research Fellow

July 2025 – Oct 2025
African Society for Bioinformatics and Computational Biology (ASBCB): Project - BrainRoute
  • Built BrainRoute, a machine learning-based tool for predicting Blood-Brain-Barrier (BBB) permeability of small molecules, utilizing molecular structure data to facilitate drug discovery for neurological diseases.
  • Developed machine learning models to predict Blood-Brain-Barrier(BBB) permeability of small molecules from molecular structures, achieving 94% accuracy with F1 of 0.94 and AUC-ROC of 0.98 on best model.
  • Implemented and optimized K-Nearest Neighbors and XGBoost classifiers for deployment in a web application enabling real-time BBB prediction.
  • Built a curated database(BrainRoute-db) of predicted molecules with permeability scores to facilitate public access of data for drug discovery researchers.

Codeathon Research Fellow

July 2024 – Oct 2024
African Society for Bioinformatics and Computational Biology (ASBCB): Project - Dengue-Drug
  • Developed machine learning classification model achieving 94% accuracy (F1: 0.85, Recall: 0.79) for predicting bioactive compounds against dengue virus.
  • Collaborated with team to conduct molecular docking studies using AutoDock Vina and molecular dynamics simulations (100ns) with GROMACS.
  • Performed comprehensive ADMET profiling and MMPBSA calculations to assess drug-likeness and binding energetics of predicted inhibitors.
  • Co-authored publication in Frontiers in Chemistry (Impact Factor: 5.5) presenting integrative computational drug discovery approach.

Machine Learning Engineer Intern

July 2023 – Feb 2024
Terminativ Ltd
  • Engineered automated web crawling pipeline using Python (Selenium, Beautiful Soup) that collected and preprocessed data from over 3,000,000 webpages for NLP applications.
  • Fine-tuned large language model on curated dataset to provide career guidance and scholarship information, improving response relevance and accuracy by 20%.
  • Implemented data validation and quality control measures to ensure training data integrity across diverse web sources.

Academic Background

Education

University of Buea

Buea, Cameroon
Expected July 2026

Masters of Science. Data Science

Coursework: Machine Learning, Big Data Processing, Data Mining, Information Visualization, Advanced Object-Oriented Programming, Database Management, Research Methodology and Scientific Writing

University of Buea

Buea, Cameroon
July 2024

Bachelors of Engineering. Software Engineering

Coursework: Data Structures and Algorithms, Machine Learning and AI, Database Management, Operating Systems